Every two years, something extraordinary happens in the watch industry. Watch companies from every segment participate in Only Watch, creating one-of-a-kind timepieces that are donated and auctioned off, with 100 percent of the proceeds going to fund research into muscular dystrophy.

“With Only Watch, everyone creates beauty to do good, meaning in this case supporting the work of dozens of researchers around the world, financing studies, purchasing material, creating biotech companies in the chemistry and biology sector…to bring this science to the clinic and one day maybe to find a cure,” says founder Luc Pettavino, who lost his son to muscular dystrophy. “We have done a lot already and are conscious that there is still much to be done and that this initiative needs, more than ever, help and support.”

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This year is the eighth edition of Only Watch, held in Geneva in November, and so far the charity has raised more than $40 million. The most watch companies ever—54—are participating this year, and there are some spectacular lots. Here are five of the best:HYT