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Best Practices: Philanthropy
The Scientific Method
Mark Dowie
09/01/2004

Frontier Mentality
After World War II ended, Vannevar Bush, a central figure in the development of nuclear fission and the Manhattan Project as director of the Office of Scientific Research and Development, declared science “the endless frontier.” He guided the nation’s leaders and academies toward preeminence in technology that would last half a century. With that imperative, Bush persuaded the government to pump so much money into research that, to many observers, private science philanthropy seemed almost irrelevant. But some prominent philanthropists were more motivated than ever, turning their attention toward influencing public policy and pulling the government’s purse strings.

Mary Lasker, wife of the late advertising pioneer Albert Lasker and a noted donor to medical research in her own right, spearheaded a lobbying effort in 1952 that helped increase the National Cancer Institute’s annual budget from $18 million a year to $110 million. Even so, in a television interview with Edward R. Murrow in 1959, she called the amount of government money going into medical research “just a piddling.” She added: “The Department of Defense spends 185 times more on defending us against dying in a military attack than the federal government spends on research against the sure killers and cripplers of our people, like cancer and heart disease and arthritis and mental illness and a variety of other things. And you won’t believe this: Less is spent on cancer research than we spend on chewing gum!”

Questions for a Science Philanthropist

• Is this initiative bound to run into a public policy stumbling block? Would a successful discovery be a catalyst for policy change?

• How will a discovery in this field change the way we live? Will it have a positive impact on society?

• Will the research pay off in my lifetime? Can it be commercially applied? Does this really matter to me?
While a faction among philanthropists worries that the United States is in danger of losing its scientific edge, science funding in the 21st century seems headed primarily toward building the next big thing in the global economy, or perhaps the galactic sphere. Rockefeller and Carnegie believed that philanthropy should look for investment returns, and it is no accident that Allen and his kind today are devotees of the venture philanthropy school of giving. (See The Business of Philanthropy.) Many of us are intent on paving the road to invention with seed grants for wholly new concepts that could someday be ripe for privatization. If there is even the remotest possibility of financial gain from an experimental drug, microprocessor or other novel product, a savvy philanthropist will write a 2 percent or 3 percent equity provision for the donor into a grant agreement.

Visionary scientists who 10 years ago might have reflexively applied for a government grant are looking with renewed interest toward this type of private philanthropy. Not coincidentally, foundations that previously paid no attention to scientific matters are reconsidering their guidelines and supporting speculative research. If foundation funding is a fair indicator, private science philanthropy is undoubtedly on the rise. In 2000, 2.8 percent of all foundation funding went to science, mostly the general and life sciences. By 2002, the share of the foundation pie going to science had risen to 3.6 percent, with $568 million in grants to some 2,200 projects. The majority of money is slated for biological science.

Something Ventured
Paul Brainerd, founder of Aldus, sold his company in 1994 and granted one-third of the proceeds (about $130 million) to protect the environment of the Northwest. He then helped form a unique philanthropic entity called the Social Venture Partnership (SVP). With 110 partners, most of whom accumulated their wealth from applied science and technology, the SVP today works under a venture capital model to create partnerships with grantees in such areas as social service, education, health, the environment and community activism, but all with a scientific approach to their cause. Like classic venture capitalists, SVP executives communicate directly with applicants and grantees to discuss objectives, goals and specific targets of performance.

While capitalizing scientific philanthropy is embryonic, intellectual property is already a controversial scientific issue debated by many contemporary private funders. The buzzwords are “open source” and “free access.” Backers such as Gordon Moore and George Soros are hoping to reverse what they see as a lamentable trend toward secrecy and private sector ownership in science. Moore provided a $9 million seed grant that launched a scientific journal called Harold Varmus’ Public Library of Science. Soros is behind the Budapest Open Access Initiative, an international effort to make research articles in all academic fields freely available on the Internet. To date there is minimal government support for moving scientific research and discovery back into the public domain, but older, more established foundations such as Ford, Rockefeller and MacArthur have begun making sizable grants to open source and open access activists.

For those of us with the resources, the resolution and the vision, science can extend our legacies through the generations. In the 1940s, the Rockefeller Foundation began to fund programs to breed new wheat stocks in Mexico to improve agricultural output and avert famine. That effort became the Green Revolution, an international surge in the production of food crops in underdeveloped nations. While not free of controversy—critics say the Rockefeller crops require more costly fertilizers and divert power from small farmers to multinational agribusiness giants—its repercussions are still felt around the world.

Illustration by Jim Frazier.
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